La Paleo Diet ha basi scientifiche ben consolidate. Negli ultimi anni sono stati condotti e sono disponibili alla consultazione centinaia di studi su questo stile di vita. Per citarne solo alcuni:
[Paleo Diet e Diabete Mellito di Tipo 1]
Tóth C., Clemens Z. – A child with type 1 diabetes mellitus (T1DM) successfully treated with the Paleolithic ketogenic diet: A 19-month insulin freedom. Int J Case Rep Images 2015;6(12):753–758 [“Un bambino con diabete mellito di tipo 1 (T1DM) trattato con successo con la dieta chetogenica paleolitica: una libertà insulinica di 19 mesi”].
[Paleo Diet e Diabete di Tipo 2]
Jönsson T., Granfeldt Y., Ahrén B., et. al. – Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study. Cardiovasc Diabetol. 2009 Jul 16.
Otten J. et al. – Benefits of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control: a randomized controlled trial in individuals with type 2 diabetes. Diabetes Metab Res Rev. 2016 May 27.
[Paleo Diet e Sclerosi Multipla]
Wahls T., O. Scott M., Alshare Z. et al. – Dietary approaches to treat MS-related fatigue: comparing the modified Paleolithic (Wahls Elimination) and low saturated fat (Swank) diets on perceived fatigue in persons with relapsing-remitting multiple sclerosis: study protocol for a randomized controlled trial. University of Iowa, Iowa, USA. National Multiple Sclerosis Society, New York, USA. 21 December 2017.
Kouchaki E., Afarini M., Abolhassani J. et. al. – High-dose ω-3 Fatty Acid Plus Vitamin D3 Supplementation Affects Clinical Symptoms and Metabolic Status of Patients with Multiple Sclerosis: A Randomized Controlled Clinical Trial. The Journal of Nutrition, Volume 148, Issue 8, 1 August 2018, Pages 1380–1386 [La supplementazione di Vitamina D3 ad alto contenuto di acidi grassi Omega 3 influisce sui sintomi clinici e sullo stato metabolico dei pazienti con sclerosi multipla: uno studio clinico controllato randomizzato].
[Paleo Diet vs. Dieta Mediterranea]
Whalen KA, et al. Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with All-Cause and Cause-Specific Mortality in Adults. J Nutr. 2017 Apr;147(4):612-620.
Whalen, KA. – Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults. J Nutr. 2016 Jun;146(6):1217-26.
Jönsson T, et al. – A Paleolithic diet is more satiating per calorie than a mediterranean-like diet in individuals with ischemic heart disease. Nutr Metab (Lond). 2010 Nov 30;7:85.
Lindeberg S, et al. – A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia. 2007 Sep;50(9):1795-807. Epub 2007 Jun 22.
[Vitamina D e Morbo di Chron]
Bendix M., Greisen S., Dige A. et. al. – Vitamin D increases programmed death receptor-1 expression in Crohn’s disease, Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; Department of Immunology, Institute of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark. Received 2016 Nov 18; Accepted 2017 Feb 7.
[Vitamina D e Depressione]
Fond G., Faugere M., Faget-Agius C. et al. – Hypovitaminosis D is associated with negative symptoms, suicide risk, agoraphobia, impaired functional remission, and antidepressant consumption in schizophrenia. Eur Arch Psychiatry Clin Neurosci. 4 August 2018 [L’ipovitaminosi D è associata a sintomi negativi, al rischio di suicidio, agorafobia e consumo di antidepressivi nella schizofrenia].